Table IV.
Genotype and allele frequencies of WRN Cys1367Arg single-nucleotide polymorphism by gender in the case and control groups for skull base chordomas.
| Gender | Genotypea | Cases, n (%) | Controls, n (%) | P-value | 95% CI |
|---|---|---|---|---|---|
| Male | G/A | 8 (23.5) | 19 (54.3) | 0.009 | 0.092–0.729 |
| A/A | 26 (76.5) | 16 (45.7) | |||
| G 177 Freq. | 0.12 | 0.32 | 0.006 | 0.115–0.719 | |
| Female | G/A | 11 (36.7) | 5 (16.7) | 0.080 | 0.860–9.745 |
| A/A | 19 (63.3) | 25 (83.3) | |||
| G 177 Freq. | 0.18 | 0.08 | 0.107 | 0.802–7.607 |
a
There was no G/G genotype in neither of the two groups.
Freq., allele frequency; CI, confidence interval.