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. 2014 May 21;2(4):549–554. doi: 10.3892/br.2014.286

Table I.

Characteristics of the case-control studies included in the meta-analysis.

First author Year Country/region Racial descent Source of controls Case, n Control, n Genotype distribution P-value HWEa Pathology
Case, n Control, n
GG GA AA GG GA AA
Yu 2003 China Asian Population-based 321 345 68 157 96 58 177 110 0.354 ESCC
Zhang 2003 China Asian Population-based 120 183 11 74 35 38 102 43 0.118 ESCC
Casson 2005 Canada Caucasian Hospital-based 56 95 12 27 17 35 52 8 0.063 EA
Geddert 2005 Germany Caucasian Hospital-based 56 253 16 26 14 63 136 54 0.224 EA
Jain 2007 India Asian Hospital-based 151 201 22 76 53 37 111 53 0.114 Mixed
Akbarib 2009 Iran Caucasian NA 279 807 72 126 81 161 376 270 0.149 ESCC
Akbaric 2009 Iran Caucasian NA 465 561 97 238 130 107 290 164 0.290 ESCC
Liu 2010 USA Caucasian Hospital-based 299 450 79 154 66 128 215 107 0.369 EA
Kurmanov 2010 Kazakhstan Caucasian Population-based 98 86 19 42 37 24 46 16 0.463 ESCC
Hussain 2011 India Asian Population-based 151 151 20 99 32 56 72 23 0.986 ESCC
Djansugurova 2013 Kazakhstan Caucasian Healthy-based 115 100 22 49 44 28 54 18 0.363 ESCC
a

HWE in controls;

b

study 1;

c

study 2.

HWE, Hardy-Weinberg equilibrium; ESCC, esophageal squamous cell carcinoma; EA, esophageal adenocarcinoma; Mixed, ESCC and EA; NA, not available.