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. 2014 Jun 10;9(6):e98459. doi: 10.1371/journal.pone.0098459

Figure 9. Protection of HMEC-1 cells from TNF-induced apoptosis by adenosine or detaNO is dependent on PGC-1α.

Figure 9

(A) Apoptosis assayed by counting of DAPI-stained cells on glass coverslips after 72 h incubation with TNFα±Ado or detaNO in either control or PGC-1α siRNA-transfected cells (PGC siRNA). Differing letters denote significant between-group differences, experiment was repeated 3 times. (B) Western blot of expression of cleaved (activated) caspase-3 in cells treated similarly as in panel (A).