Table 2. Concentration of insulin, C-reactive protein (CRP), adiponectin and leptin in the saliva supernatant of 744 children by body weight category and sex.

	Probe	Insulin	CRP	Adiponectin	Leptin
	Parameter	(median, intraquartile range)	(median, intraquartilerange)	(median, intraquartile range)	(median, intraquartile range)
	Units	pg/ml saliva	pg/ml saliva	pg/ml saliva	pg/ml saliva
Underweight (186)	M(64)	39.17, 48.63	56.64, 92.32	4,421, 6,424	0.01, 5.31
	F(122)	34.30, 38.02	61.99, 182.74	5,060, 4,573	0.01, 3.22
Normal (186)	M(93)	39.39, 45.38	73.01, 153.75	4,220, 5,303	1.06, 4.77
	F(93)	44.70, 54.38	77.15, 186.95	3,994, 5,052	0.63, 4.61
Overweight (186)	M(93)	80.39, 88.74	177.46, 311.93	2,402, 3,785	1.06, 3.26
	F(93)	76.25, 87.13	281.39, 516.54	3,322, 3,693	2.41, 5.03
Obese (186)	M(93)	112.98, 125.09	429.44, 668.52	2,548, 2,779	3.16, 6.40
	F(93)	143.50, 150.24	443.13, 1033.29	3,062, 3,752	3.70, 6.41
Wilcoxon regression p	Age	0.107	0.083	0.373	1.000
	Sex	0.337	0.028	0.471	1.000
	Overweight	<0.0001	<0.0001	0.001	0.408
	Obese	<0.0001	<0.0001	<0.0001	<0.0001
	Underweight	0.157	0.266	0.142	1.000

Summary statistics are median, interquartile range (N subjects). Values recorded for sixteen additional probes tested are in Table S3 in File S1. Probability levels for age, sex, overweight, obese and underweight were computed by Wilcoxon regression relative to normal healthy weight children.