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. 2014 Jun 10;9(6):e99080. doi: 10.1371/journal.pone.0099080

Table 2. Change in expression of neurite inhibitory and axon growth/guidance genes 24 h following spinal cord injury at P28.

SYMBOL GENE DESCRIPTION FOLD
NEURITE INHIBITION/MYELIN
Efna4 ephrin-A4 5.0
Arhgap6 Rho GTPase activating protein 6 3.1
Gmip GEM interacting protein encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. 3.0
Novel similar to SMPD3 sphingomyelin phosphodiesterase 2.4
Novel similar to OPHN1 oligophrenin 1,encodes Rho-GTPase-activating protein 2.3
Mpz myelin protein zero 1.8
Rtn4 Nogo, myelin inhibitory factor 1.2
Mog myelin oligodendrocyte glycoprotein −1.7
Mag myelin associated glycoprotein −1.8
Arhgef10 Rho guanine nucleotide exchange factor (GEF) 10 −2.0
Arhgap35 Rho GTPase activating protein 35 −2.1
Mbp myelin basic protein −2.2
Plp1 proteolipid protein 1 −2.4
AXON GROWTH & GUIDANCE
Hhipl2 HHIP-like 2, hedgehog interacting protein-like 2 6.5
Sgsm3 small G protein signaling modulator 3 4.5
Slit3 slit homolog 3 (Drosophila) interacts with Robo; axon repellent 4.0
Novel similar to DNAH7 dynein, axonemal, heavy chain 3.1
Robo3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 3.0
Mical1 microtubule assoc monoxygenase, calponin & LIM domain containing 1 2.3
Serpinf1 serpin peptidase inhib, clade F α-2 antiplasmin, pigment epithelium factor) 2.3
Tgfb3 transforming growth factor, β 3, regulator of ECMs and integrins 2.2
Ntn5 netrin 5 2.1
Tcerg1l transcription elongation regulator 1-like 2.0
Elmo3 engulfment and cell motility 3 2.0
Cntn2 contactin 2 (axonal) [Source:HGNC Symbol;Acc:2172] −2.0
Sema4f sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) −2.0
Astn1 astrotactin 1, neuronal adhesion molecule required for glial-guided migration of young postmitotic neuroblasts, previously described in developing brain −2.1
Olig2 oligodendrocyte lineage transcrip factor 2, enhances myelination after SCI −2.1
Pak7 p21 protein (Cdc42/Rac)-activated kinase 7 −2.3
Plekhb1 pleckstrin homology domain containing, family B (evectins) member 1 −2.4
Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain TMand short cytoplasmic domain, (semaphorin) 5A −2.4
Sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted −2.5
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 −2.9
Gas7 growth arrest-specific 7, neurite outgrowth in some cultured neurons −7.7

Change in expression of neurite inhibitory and axon growth/guidance genes in rostral spinal cord 24 h following spinal cord injury at P28. Note that most of the myelin inhibitory factor genes have not changed their expression in response to injury (fold <2).