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. 2014 Jun 10;9(6):e99080. doi: 10.1371/journal.pone.0099080

Table 5. Genes that changed most in expression (±≥10 FOLD) 24 h following spinal cord injury at P28.

SYMBOL GENE DESCRIPTION FOLD
MOST UPREGULATED GENES
IMMUNE & INFLAMMATORY
Novel C-C motif chemokine similar to CCL8 and CCL13 322
Dok3 docking protein 3 266
Novel C-C motif chemokine similar to CCL2, CCL7, CCL8, CCL11 and CCL13 197
Pstpip1 proline-serine-threonine phosphatase interacting protein 1 167
Lrrc33 leucine rich repeat containing 33 Official name NRROS 160
Novel similar to TARM1 T cell-interacting, activating receptor on myeloid cells 1 22
Il1b interleukin 1, β 20
Vav1 VAV1 guanine nucleotide exchange factor 17
Osmr oncostatin M receptor 14
Lgals4 lectin, galactoside-binding, soluble, 4 14
Amh anti-Mullerian hormone 12
Marco macrophage receptor with collagenous structure 12
Igsf22 immunoglobulin superfamily, member 22 12
Novel LOC100020928 C-C motif chemokine similar to CCL3 and CCL4 10
BLOOD-RELATED
Novel similar to HPR, haptoglobin-related protein 99
Novel similar to TARM1 T cell-interacting, activating receptor on myeloid cells 1 22
EXTRACELLULAR MATRIX
Olfm4 olfactomedin 4, ECM glycoprotein that facilitates cell adhesion. 480
METALLOTHIONINE
Mmp1 matrix metallopeptidase 1 (interstitial collagenase) 104
PROTEOGLYCAN
Papln papilin, proteoglycan-like sulfated glycoprotein 152
ACTIN, MYOSIN & RELATED
Trdn triadin 206
Myl1 myosin, light chain 1, alkali; skeletal, fast 139
Mylpf myosin light chain, phosphorylatable, fast skeletal muscle 22
Myh4 myosin, heavy chain 4, skeletal muscle 18
TRANSPORTERS
Slc23a3 solute carrier family 23, sodium-dependent vitamin C transporter 3 12
DEVELOPMENT & STRUCTURE
fuz fuzzy homolog (Drosophila) cell polarity, ciliogenesis & cell movement. 21
hoxb1 homeobox B1, transcription factor role in morphogenesis 12
des desmin 12
MEMBRANE
Novel novel protein with potential transmembrane domains 254
Novel novel protein with potential transmembrane domains 241
Tmem106a transmembrane protein 106A 157
ENZYMES & METABOLISM
Pstpip1 proline-serine-threonine phosphatase interacting protein 1 167
Novel similar to ATP13A5 ATPase type 13A5 23
MISCELLANEOUS
Ttc40 tetratricopeptide repeat domain 40 89
ZINC FINGER
Novel similar to ZC3H13 zinc finger CCCH-type containing 13 352
MOST DOWN REGULATED GENES
Itga4 integrin, α 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) −57
Novel similar to CLCNKA/CLCNKB chloride channel −27
Igfbpl1 insulin-like growth factor binding protein-like 1 −11
Gxylt2 glucoside xylosyltransferase 2 −16