Table 1. Relationship between APE1 expression and clinicopathological parameters.
| Characteristic | APE1 low-level | APE1 high-level | ||
| expression (n = 62) | expression (n = 177) | |||
| No. of patients (%) | No. of patients (%) | p-value | ||
| Age (years) | 0.301 | |||
| <50 | 30 (48.4) | 100 (76.9) | ||
| ≥50 | 32 (51.6) | 77 (43.5) | ||
| T stage | 0.159 | |||
| T1-T2 | 57 (91.9) | 170 (96.6) | ||
| T3-T4 | 5 (8.1) | 6 (3.4) | ||
| Lymph node metastasis | 0.448 | |||
| Negative | 42 (67.7) | 110 (62.1) | ||
| Positive | 20 (32.3) | 67 (37.9) | ||
| Estrogen receptor | 0.022 | |||
| Negative | 25 (40.3) | 43 (24.3) | ||
| Positive | 37 (59.7) | 134 (75.7) | ||
| Progesterone receptor | 0.042 | |||
| Negative | 28 (45.2) | 53 (29.9) | ||
| Positive | 34 (54.8) | 124 (70.1) | ||
| HER2 | 0.751 | |||
| Negative | 44 (71.0) | 120 (67.8) | ||
| Positive | 18 (29.0) | 57 (32.2) | ||
| Histologic grade | 0.263 | |||
| I | 24 (38.7) | 56 (31.6) | ||
| II | 22 (35.5) | 84 (47.5) | ||
| III | 16 (25.8) | 37 (20.9) | ||
| Lymphovascular invasion | 0.366 | |||
| Yes | 47 (75.8) | 118 (66.7) | ||
| No | 15 (24.2) | 58 (32.8) | ||
| Uncertain | 0 (0) | 1 (0.6) | ||
| Ki-67 | ||||
| <14% | 37 (59.7) | 114 (64.4) | 0.506 | |
| ≥14% | 25 (40.3) | 63 (35.6) | ||
| Molecular subtype | 0.000 | |||
| Luminal A | 28 (45.2) | 109 (61.6) | ||
| Luminal B | 10 (16.1) | 30 (16.9) | ||
| HER2 | 7 (11.3) | 26 (6.8) | ||
| Basal-like | 17 (27.4) | 12 (6.7) |