Table 1.

Patient characteristics, including physical age (years); menarche age (years); duration of contraceptive use (months); blood pressure profile (mmHg); BMI (kg/m²); lipid profile (mmol/L) CV risk indices of the control group and the case group (hormonal contraceptive group)

Test parameter	Control group (n=24)	Case group (n=71)	P-value
Physical age (years)	29.25±8.09	30.93±5.84	0.522
Menarche age (years)	16.07±2.56	16.38±2.80	0.859
Duration of use (months)	–	60.08±8.04	–
SBP (mmHg)	113.04±1.89	117.75±15.88	0.088
DBP (mmHg)	68.75±1.81	78.80± 14.02	0.006*
BMI (kg/m2)	21.73±0.75	25.34±4.4	0.001*
TC (mmol/L)	3.35±0.62	4.07±0.91	0.002*
TG (mmol/L)	0.66±0.24	0.81±0.44	0.466
HDLC (mmol/L)	1.31±0.25	1.33±0.34	0.768
LDLC (mmol/L)	1.74±0.57	2.38±0.84	0.003*
VLDLC (mmol/L)	0.31±0.11	0.37±0.20	0.466
TC/HDLCa	2.63±0.13	3.22±0.99	0.300
LDLC/HDLCb	1.39±0.56	1.92±0.86	0.018*
Log (TG/HDLC)c	−0.33±0.25	−0.25±0.25	0.393

Notes:

^aCastelli risk index I

^bCastelli risk index II

^catherogenic risk index

^*P<0.05; reference intervals: TC =3.60−6.20 mmol/L; TGs =0.40−2.25 mmol/L; direct HDLC = 1.03−1.55 mmol/L; LDLC = 0−3.90 mmol/L; VLDLC <0.65 mmol/L; Castelli risk =0.00−4.40; blood pressure =110/70 mmHg; BMI (kg/m²) <18.5 (underweight), 18.5−24.9 (normal weight), >25 (obesity); atherogenic risk index: <0.11 (low risk), 0.11−0.21 (intermediate risk), >0.21 (increased risk).

Abbreviations: BMI, body mass index; CV, cardiovascular; DBP, diastolic blood pressure; HDLC, high-density lipoprotein cholesterol; LDLC, low-density lipoprotein cholesterol; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; VLDLC, very-low-density lipoprotein cholesterol.