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. 2014 Jun 3;9:2803–2813. doi: 10.2147/IJN.S62806

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© 2014 Lee et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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In vitro anti-tumor efficacy in PC-3 cells.

Notes: Taxotere^® (Sanofi S.A., Paris, France) and PS-PDLLA/DCT NPs at 1 nM, 10 nM, and 100 nM DCT were incubated for (A) 48 and (B) 72 hours. An MTS-based assay was performed to assess cell viability (%). Each point indicates the mean ± SD (n≥3). *P<0.05 compared to the Taxotere group.

Abbreviations: DCT, docetaxel; MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium; NP, nanoparticle; PS-PDLLA, poly(styrene)-b-poly(DL-lactide); SD, standard deviation.