Figure 2.
Serum inhibition of the cellular uptake of liposomes in HeLa, HCC1954, MDA-MB-468, and COS-7 cells. 1,5-dihexadecyl N,N-diglutamyl-lysyl-L-glutamate (GGLG) or maleimide-modified (M-)GGLG liposomes (72 μg/mL) were incubated with cells in 10% fetal bovine serum (FBS)-containing or serum-free medium for 2 hours at 37°C.
Notes: Data represent the percentage of the cellular uptake efficiency in 10% FBS-containing medium to that in serum-free medium. Error bars represent the standard error of the mean; n=6; *P<0.01. 100% indicates the level of cellular uptake efficiency of liposomes in serum-free medium at 37°C.