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. Author manuscript; available in PMC: 2014 Jun 10.
Published in final edited form as: Leuk Res. 2010 Oct 15;35(4):526–533. doi: 10.1016/j.leukres.2010.09.009

Table 3. Cox regression model for predicting survival and complete remission duration (CRD) in Patients with Acute Myeloid Leukemia and Acute lymphoblastic leukemia.

Beta Standard
Error
t-value Wald
Statistic
P-value
Univariate Survival as predicted by
proteasome protein in AML
In all patients 0.0003 0.0001 4.4383 19.6988 <0.00001
In Intermediate cytogenetic group 0.000190 0.000086 2.222028 4.937406 0.026
In poor Cytogenetic group 0.000298 0.000087 3.418611 11.68690 0.0006

Multivariate in AML patients
Proteasome 0.0002 0.0001 3.0434 9.2622 0.002
Cytogenetic grouping 0.7860 0.1859 4.2286 17.8812 <0.00001
Age grouping (<70 vs >70) 0.6489 0.1986 3.2673 10.6751 0.001
Performance status (<2 vs >2) 0.6099 0.2130 2.8631 8.1974 0.004

CRD in AML
Ch-L/P 0.2956 0.1678 1.7619 3.1041 0.08
Cas-L/P 0.1460 0.0821 1.7774 3.1591 0.08

Univariate, survival in ALL
Proteasome 0.00001 0.0000 1.6713 2.7934 0.09
Ch-L/P −1.3914 0.6323 −2.2005 4.8422 0.03
Cas-L/P −0.7028 0.3980 −1.7661 3.1191 0.08

Univariate, CRD in ALL
Ubiquitin 0.0051 0.0027 1.9299 3.7247 0.05
Ch-L/P −1.1975 0.6623 −1.8083 3.2699 0.07
Cas-L/P −1.8295 0.7336 −2.4939 6.2195 0.01