Table 3. Cox regression model for predicting survival and complete remission duration (CRD) in Patients with Acute Myeloid Leukemia and Acute lymphoblastic leukemia.
Beta | Standard Error |
t-value | Wald Statistic |
P-value | |
---|---|---|---|---|---|
Univariate Survival as predicted by proteasome protein in AML |
|||||
In all patients | 0.0003 | 0.0001 | 4.4383 | 19.6988 | <0.00001 |
In Intermediate cytogenetic group | 0.000190 | 0.000086 | 2.222028 | 4.937406 | 0.026 |
In poor Cytogenetic group | 0.000298 | 0.000087 | 3.418611 | 11.68690 | 0.0006 |
| |||||
Multivariate in AML patients | |||||
Proteasome | 0.0002 | 0.0001 | 3.0434 | 9.2622 | 0.002 |
Cytogenetic grouping | 0.7860 | 0.1859 | 4.2286 | 17.8812 | <0.00001 |
Age grouping (<70 vs >70) | 0.6489 | 0.1986 | 3.2673 | 10.6751 | 0.001 |
Performance status (<2 vs >2) | 0.6099 | 0.2130 | 2.8631 | 8.1974 | 0.004 |
| |||||
CRD in AML | |||||
Ch-L/P | 0.2956 | 0.1678 | 1.7619 | 3.1041 | 0.08 |
Cas-L/P | 0.1460 | 0.0821 | 1.7774 | 3.1591 | 0.08 |
| |||||
Univariate, survival in ALL | |||||
Proteasome | 0.00001 | 0.0000 | 1.6713 | 2.7934 | 0.09 |
Ch-L/P | −1.3914 | 0.6323 | −2.2005 | 4.8422 | 0.03 |
Cas-L/P | −0.7028 | 0.3980 | −1.7661 | 3.1191 | 0.08 |
| |||||
Univariate, CRD in ALL | |||||
Ubiquitin | 0.0051 | 0.0027 | 1.9299 | 3.7247 | 0.05 |
Ch-L/P | −1.1975 | 0.6623 | −1.8083 | 3.2699 | 0.07 |
Cas-L/P | −1.8295 | 0.7336 | −2.4939 | 6.2195 | 0.01 |