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. 2014 Jun 10;9(6):e99402. doi: 10.1371/journal.pone.0099402

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© 2014 Brander et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) k_cat in s⁻¹. (B) K_M in mM (C) k_cat/K_M showing the effect on total pH-dependent activity. The profiles were fitted with a Gaussian using a mean pH of 7.7 and an amplitude of 30.8 for B. subtilis cotA and 8.1 and 4.0 for B. clausii cotA, respectively. Please see File S1 for full data.