Table 3. Genotype and allele frequencies of COMT 158 G/A polymorphism among vitiligo patients and controls and association with the risk of vitiligo.
| COMT genotype | Vitiligo patients N = 89 N (%) | Controls N = 90 N (%) | p-value | COMT alleles | Vitiligo (%) | Control (%) | p-value | Odds ratio (95% CI) |
| GG | 23(25.8) | 27(30) | 0.5 | G | 52.8 | 52.8 | 1.0 | 1.02 |
| GA | 48(53.9) | 41(45.6) | A | 47.2 | 47.2 | (0.6–1.6) | ||
| AA | 18(20.2) | 22(24.4) | *HWE | |||||
| GA+AA | 66(74.1) | 63(70) | 0.5 | x2 | 0.79 | 0.67 |
Data are reported as number with percent in parentheses.
*HWE = Hardy-Weinberg equilibrium, 95% CI: 95% confidence interval.