Table 4. The frequency of the wild and combined genotypes of the T/C exon 9 polymorphism of CAT gene among vitiligo patients and the association with risk of vitiligo.
Variable | Vitiligo patients N = 89 | Wild type (TT) N (%) | Combined genotypes (TC+CC) N (%) | Odds ratio (95% CI) | p-value |
Onset | |||||
Early1 | 27 | 5(18.5) | 22(81.5) | 1.6 | 1.0 |
Late | 62 | 5(8.1) | 57(91.9) | (0.17–15.9) | |
Family history | |||||
Yes | 26 | 6(23.1) | 20(76.9) | 0.23 | 0.1 |
No | 63 | 7(11.1) | 56(88.8) | (0.03–1.5) | |
Gender | |||||
Male | 28 | 4(14.2) | 24(85.7) | 0.32 | 0.3 |
Female | 61 | 10(16.4) | 51(83.6) | (0.05–2.1) | |
Stress | |||||
Yes | 43 | 13(30.2) | 30(69.8) | 0.16 | 0.1 |
No | 46 | 10(21.7) | 36(78.3) | (0.01–1.5) |
Data are reported as number with percent in parentheses. 95% CI: 95% confidence interval.
Early onset subgroup means vitiligo occurred before 20 years old and the late-onset subgroup means vitiligo occurred after 20 years old.