Figure 4. Chronic stress induces fear generalization to a novel context.
(A) Chronic stress enhanced freezing to context prior to the first CS presentation when tested for extinction memory, while all groups showed similar levels of freezing during the first CS presentation. There was no impact of test context (SAME and NOVEL collapsed within each stress condition; n=8–10/group). (B) Fear Generalization. STR displayed increased freezing to the context prior to trial 1, regardless of test context (SAME or NOVEL; n=4–5/group). Data are represented as mean ± SEM; **p=0.01 vs. CON.