Table 2.
Twenty genes displaying the highest change in expression levels in Na+/K+/2Cl- cotransporter 1 depleted KYSE170 cells
| Gene Symbol | Gene ID | Gene Name | Fold Change |
| Upregulated Genes | |||
| C18orf34 | NM_001105528 | Chromosome 18 open reading frame 34 | 155.49 |
| KCNA6 | NM_002235 | Potassium voltage-gated channel, shaker-related subfamily, member 6 | 140.4 |
| CCDC147 | NM_001008723 | Coiled-coil domain containing 147 | 105.98 |
| C20orf202 | NM_001009612 | Chromosome 20 open reading frame 202 | 86.17 |
| A1CF | NM_138933 | APOBEC1 complementation factor | 70.98 |
| SH3GL2 | NM_003026 | SH3-domain GRB2-like 2 | 70.93 |
| PTGFR | NM_001039585 | Prostaglandin F receptor (FP) | 66.99 |
| NDN | NM_002487 | Necdin homolog (mouse) | 66.45 |
| INPP5D | NM_001017915 | Inositol polyphosphate-5-phosphatase, 145 kDa | 52.83 |
| CYP2E1 | NM_000773 | Cytochrome P450, family 2, subfamily E, polypeptide 1 | 52.44 |
| AGBL3 | NM_178563 | ATP/GTP binding protein-like 3 | 50.88 |
| UBTFL1 | NM_001143975 | Upstream binding transcription factor, RNA polymerase I-like 1 | 47.88 |
| PADI2 | NM_007365 | Peptidyl arginine deiminase, type II | 46.83 |
| CCR1 | NM_001295 | Chemokine (C-C motif) receptor 1 | 44.86 |
| ARC | NM_015193 | Activity-regulated cytoskeleton-associated protein | 44.41 |
| COLEC10 | NM_006438 | Homo sapiens collectin sub-family member 10 (C-type lectin) | 44.28 |
| DNAH6 | NM_001370 | Dynein, axonemal, heavy chain 6 | 41.96 |
| BOLL | NM_033030 | Bol, boule-like (Drosophila) | 41.31 |
| CORO2B | NM_006091 | Coronin, actin binding protein, 2B | 41.04 |
| MUC7 | NM_152291 | Mucin 7, secreted | 36.97 |
| Downregulated Genes | |||
| NPFFR1 | NM_022146 | Neuropeptide FF receptor 1 | -54.97 |
| LRRFIP1 | NM_001137550 | Leucine rich repeat (in FLII) interacting protein 1 | -44.72 |
| PPIL6 | NM_173672 | Peptidylprolyl isomerase (cyclophilin)-like 6 | -44.46 |
| CRHR2 | NM_001883 | Corticotropin releasing hormone receptor 2 | -39.78 |
| CMTM2 | NM_144673 | CKLF-like MARVEL transmembrane domain containing 2 | -39.62 |
| C5 | NM_001735 | Complement component 5 | -39.13 |
| KCNMA1 | NM_001014797 | Potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | -38.59 |
| HESX1 | NM_003865 | HESX homeobox 1 | -33.03 |
| SLC22A2 | NM_003058 | Solute carrier family 22 (organic cation transporter), member 2 | -32.49 |
| WNT8B | NM_003393 | Wingless-type MMTV integration site family, member 8B | -32.17 |
| GRIA1 | NM_000827 | Glutamate receptor, ionotropic, AMPA 1 | -31.27 |
| ZNF367 | NM_153695 | Zinc finger protein 367 | -30.04 |
| GPR128 | NM_032787 | G protein-coupled receptor 128 | -29.88 |
| SLC12A2 | NM_001046 | Solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | -28.92 |
| KCNG2 | NM_012283 | Potassium voltage-gated channel, subfamily G, member 2 | -28.3 |
| ECT2L | NM_001077706 | Epithelial cell transforming sequence 2 oncogene-like | -27 |
| ERMN | NM_020711 | Ermin, ERM-like protein | -26.61 |
| DPP10 | NM_020868 | Dipeptidyl-peptidase 10 (non-functional) | -26.58 |
| TSPAN7 | NM_004615 | Tetraspanin 7 | -25.54 |
| APOA1 | NM_000039 | Apolipoprotein A-I | -25.21 |