Table 5.
Analysis of Helicobacter pylori gene expression in adenocarcinoma gastric tissues with clinico-epidemiological parameters n (%)
| Clinico-epidemiological Characteristics | Total cases, n | ureC positive | P | cagA positive | P | Hp +ve | P |
| Adenocarcinoma | 65 | 33 (50.8) | < 0.0011 | 17 (26.2) | < 0.0011 | 34 (52.3) | < 0.0011 |
| 0.7082 | 0.3122 | 0.3452 | |||||
| Age (median 55 yr; range: 22-90 yr) | |||||||
| < 55 | 31 | 14 (45.2) | 0.388 | 10 (32.3) | 0.285 | 15 (48.4) | 0.546 |
| ≥ 55 | 34 | 19 (55.9) | 7 (20.6) | 19 (55.9) | |||
| Gender | |||||||
| Male | 42 | 22 (52.4) | 0.725 | 10 (23.8) | 0.561 | 23 (54.8) | 0.592 |
| Female | 23 | 11 (47.8) | 7 (30.4) | 11 (47.8) | |||
| Types | |||||||
| Diffuse | 44 | 24 (54.5) | 0.378 | 13 (29.5) | 0.368 | 25 (56.8) | 0.292 |
| Intestinal | 21 | 9 (42.9) | 4 (19) | 9 (42.9) | |||
| Habits3 | |||||||
| Tobacco chewers | 24 | 19 (79.2) | < 0.001 | 12 (50) | 0.001 | 19 (79.2) | 0.001 |
| Tobacco non-chewers | 41 | 14 (34.1) | 5 (12.2) | 15 (36.6) | |||
| Tobacco smokers | 20 | 10 (50) | 0.934 | 8 (40) | 0.090 | 11 (55) | 0.772 |
| Tobacco non-smokers | 45 | 23 (51.1) | 9 (20) | 23 (51.1) | |||
| Alcoholic | 16 | 9 (56.2) | 0.614 | 4 (25) | 0.904 | 9 (56.3) | 0.716 |
| Non-alcoholic | 49 | 24 (49) | 13 (26.5) | 25 (51) | |||
| Multiple habits | 16 | 9 (56.2) | 0.614 | 6 (37.5) | 0.234 | 9 (56.3) | 0.716 |
Pre-cancer vs adenocarcinoma;
Normal vs adenocarcinoma;
Tobacco chewing habits include betel quid, areca nut, and/or pan masala use; multiple habits include two or more of any tobacco and/or alcohol habits.