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L7Cre;Vgatflox/flox mice exhibit severe motor impairments. A, Sample footprints from Vgatflox/flox and L7Cre;Vgatflox/flox mice. B, Quantification of footprints reveals significantly shorter stride lengths and stance widths in L7Cre;Vgatflox/flox mice compared with the control littermates. Sway length was not significantly different. C, Accelerating rotarod performance was significantly diminished in L7Cre;Vgatflox/flox mice compared with the control littermates; ***p < 0.001.
