Fig. 1.

Biliverdin inhibits C5aR expression. RAW Mφ were treated BV ± LPS for 24 h. (A) Gene and (B) cell surface expression of C5aR in RAW Mφ. (C) Cell surface expression of C5aR in BMDM Mφ treated with BV and LPS for 24 and 48 h. Data are representatives of three independent experiments. Value represents mean ± S.E. n = 3/group, ^∗P < 0.05 vs. non LPS control (0.01% DMSO) at 24 h and 48 h and ^&P < 0.05 vs. LPS control at 24 and 48 h.