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Biliverdin attenuates complement associated pro-inflammatory cytokines. mRNA expression of TNF-α (A) and IL-6 (B) and protein concentration of TNF-α (C) and IL-6 (D) were analyzed in RAW 264.7 macrophages, incubated with BV ± LPS for 24 h. The data are representative of two independent experiments. Value represents mean ± S.E. n = 3/group, ∗P < 0.05 vs. no LPS control (0.01% DMSO) and &P < 0.05 vs. LPS control.
