Table 2.
Objectively measured health behaviours by study group and between-group differences at 1 year in the ADDITION-Plus trial
| Health behaviours | Comparison group | Intervention group | Difference between groups (95% CI) | p value |
|---|---|---|---|---|
| PAEE, kJ kg−1 day−1a | 33.7 (15.9) (N = 212) | 35.2 (18.2) (N = 218) | +1.50 (−1.74, 4.74) | 0.36 |
| Plasma vitamin C, μmol/l | 56.2 (25.1) (N = 216) | 53.4 (25.0) (N = 218) | −3.84 (−8.07, 0.38)b | 0.07 |
| Smoking, %; cotinine validated (n/N) | 13.2 (23/174) | 17.3 (34/197) | 1.37c (0.77, 2.43) | 0.28 |
| Drug plasma level, μmol/l | ||||
| Metformin | 1,310.0 (741.7) (N = 82) | 1,190.5 (725.6) (N = 100) | −119.5 (−335.0, 95.9) | 0.28 |
| Log simvastatind | −1.07 (1.73) (N = 30) | −1.43 (1.45) (N = 42) | −0.36 (−1.10, 0.39) | 0.35 |
| Log atorvastatind | 1.07 (1.01) (N = 40) | 0.91 (1.02) (N = 32) | −0.16 (−0.63, 0.32) | 0.52 |
Values are mean SD unless otherwise stated; N is the number with data available
aPhysical activity is individually calibrated where available (n = 351), otherwise group calibrated (n = 79)
bDifference between groups is adjusted for baseline values
cResults are expressed as ORs
dResults are expressed on the natural log-scale since original variable showed substantial skewness