Table 4.

HRs (95% CI) for type 2 diabetes by duration of breast-feeding with adjustment for biochemical mediators, EPIC-Potsdam study

	Ever breast-fed		Cumulative duration of breast-feeding
	No	Yes	0	≤3 weeks	>3 weeks to <2 months	≥2 months to <6 months	≥6 months	Per additional 6 months of breast-feeding
n cases	49	177	49	31	38	66	42	226
Model I	1	0.77 (0.47, 1.25)	1	1.16 (0.62, 2.19)	0.77 (0.43, 1.41)	0.82 (0.47, 1.41)	0.47 (0.25, 0.89)	0.80 (0.61, 1.04)
Model I + HDL, LDL, triacylglycerols	1	0.88 (0.55, 1.42)	1	1.38 (0.71, 2.69)	0.93 (0.51, 1.67)	0.91 (0.53, 1.57)	0.55 (0.29, 1.02)	0.85 (0.66, 1.09)
Model I + CRP	1	0.73 (0.45, 1.18)	1	1.11 (0.59, 2.08)	0.72 (0.39, 1.32)	0.77 (0.45, 1.33)	0.47 (0.25, 0.88)	0.81 (0.62, 1.06)
Model I + fetuin-A, GGT	1	0.78 (0.48, 1.26)	1	1.24 (0.66, 2.33)	0.78 (0.43, 1.42)	0.83 (0.48, 1.42)	0.47 (0.24, 0.90)	0.81 (0.62, 1.06)
Model I + adiponectin	1	0.91 (0.57, 1.45)	1	1.64 (0.90, 3.00)	0.91 (0.51, 1.64)	0.93 (0.54, 1.59)	0.58 (0.31, 1.07)	0.84 (0.64, 1.10)
Model I + HDL, LDL, triacylglycerols + CRP + fetuin-A, GGT + adiponectin	1	0.95 (0.59, 1.53)	1	1.74 (0.91, 3.32)	1.00 (0.55, 1.83)	0.91 (0.53, 1.58)	0.62 (0.33, 1.16)	0.89 (0.68, 1.16)

GGT, γ-glutamyltransferase

Model I adjusted for age at baseline, marital status, education, occupation, smoking, sport, cycling, alcohol intake, coffee consumption, intake of red meat, intake of whole-grain bread, age at birth of last child, number of children, duration of oral contraceptive use, BMI at age of 25 years, BMI and waist circumference at baseline examination. n = 1,262