Table 1.
Clinical characteristics of the subjects based on menopausal status.
| Variable | Premenopausal (n = 319) | Postmenopausal (n = 440) | P value |
|---|---|---|---|
| Age (years) | 43.6 ± 6.3 | 57.5 ± 6.7 | <0.001 |
| Height (cm) | 159.3 ± 5.4 | 156.2 ± 5.2 | <0.001 |
| Weight (kg) | 56.0 ± 8.0 | 56.8 ± 7.3 | NS |
| BMI (kg/m2) | 22.1 ± 2.9 | 23.3 ± 2.9 | <0.001 |
| Spine T-score | 0.17 ± 1.18 | −0.93 ± 1.27 | <0.001 |
| Femur T-score | −0.02 ± 0.92 | −0.68 ± 0.94 | <0.001 |
| Calcium (mmol/L) | 2.26 ± 0.09 | 2.31 ± 0.08 | <0.001 |
| ALP (U/L) | 50.1 ± 14.1 | 66.6 ± 21.8 | <0.001 |
| Phosphorus (mmol/L) | 1.16 ± 0.16 | 1.24 ± 0.17 | <0.001 |
| Total cholesterol (mmol/L) | 4.75 ± 0.78 | 5.15 ± 0.81 | <0.001 |
| Triglycerides (mmol/L) | 1.03 ± 0.52 | 1.19 ± 0.59 | <0.001 |
| HDL-C (mmol/L) | 1.64 ± 0.40 | 1.58 ± 0.38 | <0.05 |
| hsCRP (mg/L) (median and interquartile range) |
0.39 (0.26–0.73) | 0.59 (0.36–1.21) | <0.001* |
| CTX (μg/L) | 309 ± 172 | 546 ± 265 | <0.001 |
| Osteocalcin (μg/L) | 15.40 ± 6.00 | 21.69 ± 8.58 | <0.001 |
ALP: alkaline phosphatase; BMI: body mass index; CTX: cross-linked C-terminal telopeptide; HDL-C: high density lipoprotein cholesterol; NS: not significant; TC: total cholesterol. Values are expressed as means ± standard deviations if not otherwise specified. *Analyzed using the Mann-Whitney U-test.