Table 2.
Effectiveness of ramelteon.
| Ramelteon | Ramelteon (mg/day) | Effectiveness | |||
|---|---|---|---|---|---|
| Start age | Initial dose | Maintenance dose | CGI-I | Improvement | |
| Case 1 | 9 | 2 | 2 | 2 | Reduced LPS |
| Reduced acoustic hypersensitivity | |||||
| Reduced panic attacks | |||||
|
| |||||
| Case 2 | 11 | 2 | 2 | 3 | Reduced LPS |
| Maintained sleep-wake rhythm | |||||
| Reduced hyperactivity | |||||
|
| |||||
| Case 3 | 12 | 4 | 8 | 2 | Reduced LPS |
| Increased TST | |||||
| Reduced overeating | |||||
The Clinical Global Impression-Improvement (CGI-I) Scale is used to assess the degree of symptom improvement or worsening (1: very much improved; 2: much improved; 3: moderately improved; 4: minimally improved; 5: no change; 6: minimally worse; 7: moderately worse; 8: much worse; and 9: very much worse). LPS: latency to persistent sleep; TST: total sleep time.