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. 2014 May 15;2014:914954. doi: 10.1155/2014/914954

Figure 2.

Figure 2

IL-18, IL-18BP, and IL-18R mRNA levels in normal and cancerous ovarian homogenates. Normal and cancerous ovarian samples were homogenized. The expression levels of IL-18 (a), IL-18BP (b), and IL-18R (c) mRNA were evaluated by semiquantitative RT-PCR. Quantitative evaluation of the positive PCR products was performed by densitometry. Each point represents the ratio between IL-18, IL-18BP, or IL-18R bands and β-actin bands of the same sample; n = 13 and 10 in (a), 12 and 10 in (b), and 10 and 7 in (c), for the normal and carcinoma samples, respectively. Horizontal lines indicate MEAN ± SEM. (d) Representative samples of normal (1–4) and cancerous (5–8) ovarian tissues are presented. ∗ indicates statistical significance according to t-test: *P = 0.025.