Figure 2.

Micronucleus in cytokinesis-blocked Vero-E6 and HepG2 cells, following exposure to MCLR for 24 hours. Results are expressed as the mean frequency of micronucleated binucleated cells (MNBC) per 1000 binucleated cells (BC). Mean (±SD) were obtained from three (Vero-E6) or two (HepG2) independent experiments, using duplicate cultures. Mitomycin C (MMC, 0.1 μg/mL, 24 h) was used as the positive control of the assay. ∗represents a statistically significant difference between the treated and the control cells (P < 0.05).