Table 1.
Results of DNA damage assessed by the comet assay (% of DNA in tail) in MCLR-treated Vero-E6 cells.
| MCLR (μM) | % of DNA in the comet tail | |||
|---|---|---|---|---|
| Exposure time | ||||
| 4 h | 24 h | |||
| Buffer | FPG | Buffer | FPG | |
| 0 | 4.11 ± 0.21 | 5.13 ± 0.28 | 3.29 ± 0.01 | 3.76 ± 0.42 |
| 5 | 4.21 ± 0.38 | 4.96 ± 0.42 | 3.16 ± 0.39 | 3.37 ± 0.14 |
| 10 | 3.82 ± 0.04 | 6.41 ± 0.55 | 2.74 ± 0.44 | 4.08 ± 0.21 |
| 20 | 4.77 ± 0.50 | 5.74 ± 0.75 | 3.67 ± 0.16 | 4.22 ± 0.14 |
Values are the mean (±SE) of three independent experiments. The percentage of DNA in the comet tail induced by the positive control (H2O2, 30 min) was 13.73 ± 0.62 and 22.86 ± 0.94, without and with FPG treatment, respectively.