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. 2014 May 20;106(10):2105–2114. doi: 10.1016/j.bpj.2014.04.017

Figure 3.

Figure 3

Sarcomere length dynamics at physiologic pH and in acidosis. (A) Representative traces of sarcomere length dynamics normalized to baseline of the five groups (Black = pH 7.4, White = pH 6.2). (B–D) pH 7.4 sarcomere length dynamics showing baseline sarcomere length, fractional shortening, and the relaxation parameter time from peak amplitude to 50% baseline. (E and F) pH 6.2 sarcomere length dynamics showing baseline sarcomere length and fractional shortening. (G) The change in fractional shortening from pH 6.2 to pH 7.4. n = 45–60 myocytes from six independent experiments for each group. ∗P < 0.05 from one-way analysis of variance with the Bonferroni post hoc test.