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Summary of exogenous A2 effects in EPI control (Con) and detubulated (Det) myocytes. (A) Cm decreased similarly upon detubulation in both Con and A2 myocytes. (B) In Con myocytes, application of A2 induced a significant decrease in IP amplitude but had no effect in Det myocytes. These results suggest that A2/AT1R effects on IP mostly take place in the T-system.
