Table 5.
Single node and edge differences found between MS and control groups
| Path | Type | Multiple sclerosis ( MS ) | Control (C) | Difference (95% CI) | P-value | Up/down |
|---|---|---|---|---|---|---|
| 382 ← group |
Group on node |
-9.002 |
-7.963 |
-1.04 (-1.65; -0.43) |
0.001 |
MS down-expressed |
| 10093 ← group |
Group on node |
-0.452 |
0.032 |
-0.48 (-0.93; -0.04) |
0.033 |
MS down-expressed |
| 5580 ← group |
Group on node |
-3.054 |
-2.648 |
-0.41 (-0.70; -0.11) |
0.007 |
MS down-expressed |
| 5321 ← group |
Group on node |
0.694 |
1.240 |
-0.55 (-1.00;-0.09) |
0.020 |
MS down-expressed |
| 1399 ← group |
Group on node |
4.688 |
6.126 |
-1.44 (-1.82;-1.05) |
0.000 |
MS down-expressed |
| 8613 ↔ 8612 |
Indirect |
0.001 |
-0.002 |
0.003 (0.001;0.004) |
0.038 |
MS up-associated |
| 23396 ← 8613 |
Indirect |
0.643 |
-4.981 |
5.62 (2.44; 8.81) |
0.001 |
MS up-regulated |
| 23396 ← 5880 |
Activation |
0.079 |
1.207 |
-1.13 (-1.91;-0.35) |
0.005 |
MS down-regulated |
| 23396 ← 8612 |
Indirect |
-6.219 |
-0.945 |
-5.27 (-6.62; -3.92) |
0.000 |
MS down-regulated |
| 10093 ← 8936 |
Activation |
0.576 |
0.267 |
0.31 (0.08; 0.53) |
0.007 |
MS up-regulated |
| 5581 ← 8613 |
Indirect |
0.002 |
0.953 |
-0.95 (-1.41; -0.49) |
0.000 |
MS down-regulated |
| 5581 ← 8612 |
Indirect |
1.343 |
0.104 |
1.24 (0.78; 1.70) |
0.000 |
MS up-regulated |
| 382 ← 1399 |
Directed path |
0.970 |
0.144 |
0.83 (0.19; 1.46) |
0.011 |
MS up-regulated |
| 7454 ← 5338 |
Directed path |
1.070 |
0.111 |
0.96 (0.28; 1.64) |
0.006 |
MS up-regulated |
| 5604 ← 8613 |
Directed path |
0.618 |
3.133 |
-2.52 (-4.64; -0.39) |
0.020 |
MS down-regulated |
| 23396 ← 1399 | Directed path | -0.323 | -0.755 | 0.43 (0.24; 0.62) | 0.000 | MS up-regulated |