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. 2014 Apr 30;12(5):2408–2421. doi: 10.3390/md12052408

Table 2.

Biological activities of poly-APS and their synthetic analogues.

Compound AChE Inhibition—Ki (nM) * Hemolysis (s−1 at 500 nM) ** IC50 for NSCLC (μM) ***
Poly-APS irreversible inhibition 0.05 4.41
APS3 85 0 3000
APS7 10 0.1 480
APS8 1.875 2.6 478
APS12-2 0.036 5.0 470

NSCLC, non-small cell lung cancer; * [28]; ** [31]; *** [41].