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. 2014 May 13;12(5):2922–2936. doi: 10.3390/md12052922

Figure 6.

Figure 6

Ech A protected mitochondrial functions against cardiotoxic agent-induced damage. H9c2 cells were treated with cardiotoxic agents for 1 h. Cellular and mitochondrial ATP level were measured using the mitochondrial ToxGlo assay, respectively. (A) Cardiotoxic agents reduced cellular ATP, but co-treatment with Ech A prevented this reduction. (B) Moreover, cardiotoxic agents also reduced mitochondrial ATP, but co-treatment with Ech A prevented this reduction. Four independent in vitro experiments were performed. P < 0.05 vs. cardiotoxic agent single treatment group.