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. 2014 Jun 11;8:153. doi: 10.3389/fnins.2014.00153

Figure 5.

Figure 5

Adolescent experience alters adult behavior in iboNVHL animals. (A) At postnatal day 35 (P35), iboNVHL animals were habituated to the room on the stationary arena for two 10 min sessions with a 10 min inter trial interval. Adolescence training consisted of eight trials per day for 2 days (P36 and P37). To control for noncognitive experience, a group of adolescent animals was received the same experience with the shock off. (B) During adolescence, iboNVHL animals are able to perform the task as well as saline controls. (C) Adolescence training had a positive impact on adult behavior in the active place avoidance task. iboNVHL animals that received cognitive training during adolescence performed as well as saline control animals when tested as adults. The animals that received noncognitive experience during adolescence remained impaired. Data are presented as average ± s.e.m.