Table 4.
Variable |
Total N of Patients |
Patients % (n) | Relative Risk (95% CI) |
p-Value | |
---|---|---|---|---|---|
Intervention | Usual Care |
||||
4 or more specialty mental health visits in prior 6 months | |||||
6 Months | 183 | 79.1 (72) | 29.3 (27) | 2.70 (1.73 – 4.20) | < 0.001 |
12 Months | 177 | 74.9 (67) | 30.8 (28) | 2.53 (1.63 – 3.94) | < 0.001 |
Any antidepressant medication | 0.123* | ||||
Baseline | 205 | 46.1 (47) | 49.5 (51) | 0.93 (0.63 – 1.38) | 0.722 |
6 Months | 183 | 61.5 (56) | 47.8 (44) | 1.29 (0.87 – 1.91) | 0.211 |
12 Months | 177 | 61.6 (53) | 47.3 (43) | 1.30 (0.87 – 1.95) | 0.196 |
Two or more simultaneous antidepressant medications | 0.013* | ||||
Baseline | 199 | 3.0 (3) | 7.1 (7) | 0.42 (0.11 – 1.61) | 0.204 |
6 Months | 183 | 24.2 (22) | 9.8 (9) | 2.47 (1.14 – 5.37) | 0.022 |
12 Months | 177 | 22.1 (19) | 7.7 (7) | 2.87 (1.21 – 6.83) | 0.017 |
Any antidepressant for ≥ 25 days in the past month | 0.126* | ||||
Baseline | 176 | 23.1 (21) | 18.8 (16) | 1.23 (0.64 – 2.35) | 0.539 |
6 Months | 182 | 56.0 (51) | 31.9 (29) | 1.76 (1.12 – 2.77) | 0.015 |
12 Months | 177 | 52.3 (45) | 33.0 (30) | 1.59 (1.01 – 2.52) | 0.050 |
Any antidepressant for 3 of the past 6 months at an adequate dosage† | 0.021* | ||||
Baseline | 177 | 14.3 (13) | 16.3 (14) | 0.88 (0.41 – 1.87) | 0.735 |
6 Months | 183 | 51.6 (47) | 31.5 (29) | 1.64 (1.03 – 2.60) | 0.037 |
12 Months | 168 | 57.1 (48) | 33.3 (28) | 1.71 (1.08 – 2.73) | 0.023 |
Group-by-time interaction: baseline to 12 months
Adequate dosage is the recommended starting dosage on package insert (eg, 20 mg of fluoxetine).