Table 1. Demographics and risk factors for incident aortic dissection by gender and type.
| Total (n=52) | Total (excl. Marfan’s) (n=49) | Male (n=31) | Female (n=21) | P | Type A (n=37) | Type B (n=15) | P | |
|---|---|---|---|---|---|---|---|---|
| Mean (SD) age, years | 72.0 (14.5) | 73.8 (11.5) | 67.1 (14.9) | 79.3 (10.4) | 0.002 | 72.5 (15.4) | 70.8 (12.3) | 0.70 |
| Male | 31 (59.6%) | 27 (55.1%) | 20 (54.1%) | 11 (73.3%) | 0.23 | |||
| Prior vascular disease | ||||||||
| Angina | 5 (9.6%) | 5 (10.2%) | 2 (6.5%) | 3 (14.3%) | 0.38 | 4 (10.8%) | 1 (6.7%) | 1.00 |
| Acute coronary syndrome | 5 (9.6%) | 5 (10.2%) | 3 (9.7%) | 2 (9.5%) | 1.00 | 3 (8.1%) | 2 (13.3%) | 0.62 |
| TIA | 4 (7.7%) | 3 (6.1%) | 2 (6.5%) | 2 (9.5%) | 1.00 | 1 (2.7%) | 2 (13.3%) | 0.07 |
| Stroke | 13 (25.0%) | 12 (24.5%) | 6 (19.4%) | 7 (33.3%) | 0.25 | 5 (13.5%) | 8 (53.3%) | 0.005 |
| Peripheral arterial disease | 3 (5.8%) | 2 (4.1%) | 2 (6.5%) | 1 (4.8%) | 1.00 | 2 (5.4%) | 1 (6.7%) | 1.00 |
| Risk factors | ||||||||
| Current smoker | 9 (17.3%) | 9 (18.4%) | 6 (19.4%) | 3 (14.3%) | 0.72 | 6 (16.2%) | 3 (20.0%) | 1.00 |
| Ever smoked | 32 (61.5%) | 31 (63.3%) | 21 (67.7%) | 11 (52.4%) | 0.48 | 20 (57.1%) | 12 (80.0%) | 0.20 |
| Marfan’s syndrome | 3 (5.8%) | 0 (0.0%) | 3 (9.7%) | 0 (0.0%) | 0.26 | 1 (2.7%) | 2 (13.3%) | 0.20 |
| Hypertension | 35 (67.3%) | 34 (69.4%) | 18 (58.1%) | 17 (81.0%) | 0.08 | 25 (67.6%) | 10 (66.7%) | 0.95 |
| Diabetes mellitus | 6 (11.5%) | 5 (10.2%) | 4 (12.9%) | 2 (9.5%) | 1.00 | 3 (8.1%) | 3 (20.0%) | 0.34 |
| Cardiac failure | 3 (5.8%) | 3 (6.1%) | 0 (0.0%) | 3 (14.3%) | 0.06 | 0 (0.0%) | 3 (20.0%) | 0.02 |
| Atrial fibrillation | 8 (15.4%) | 8 (16.3%) | 5 (16.1%) | 3(14.3%) | 1.00 | 4 (10.8) | 4 (26.7%) | 0.21 |
| Medications | ||||||||
| Statin | 15 (28.8%) | 14 (28.6%) | 9 (29.0%) | 6 (28.6%) | 0.97 | 8 (21.6%) | 7 (46.7%) | 0.07 |
| Aspirin | 19 (36.5%) | 19 (38.8%) | 10 (32.3%) | 9 (42.9%) | 0.44 | 11 (29.7%) | 8 (53.3%) | 0.11 |
| Other antiplatelet agents | 2 (3.8%) | 2 (4.1%) | 1 (3.2%) | 1 (4.8%) | 1.00 | 1 (2.7%) | 1 (6.7%) | 0.50 |
| Warfarin | 3 (5.8%) | 1 (2.0%) | 3 (9.7%) | 0 (0.0%) | 0.26 | 1 (2.7%) | 2 (13.3%) | 0.20 |
| Antihypertensives | ||||||||
| 0 | 17 (32.7%) | 16 (32.7%) | 13 (41.9%) | 4 (19.0%) | 13 (35.1%) | 4 (26.7%) | ||
| 1 | 11 (21.2%) | 11 (22.4%) | 4 (12.9%) | 7 (33.3%) | 9 (24.3%) | 2 (13.3%) | ||
| 2 | 14 (26.9%) | 14 (28.6%) | 9 (29.0%) | 5 (23.8%) | 10 (27.0%) | 4 (26.7%) | ||
| 33 | 10 (19.2%) | 8 (16.3%) | 5 (16.1%) | 5 (23.8%) | 0.17 | 5 (13.5%) | 5 (33.3%) | 0.39 |
Categorical data is expressed as n (%) throughout. TIA, transient ischemic attack.