Fig. 2.

Tissue slice cytotoxicity assays in head and neck squamous cell carcinoma patient specimens cultured with varying concentrations of CNTO3899 (0, 50, 100, and 200 µg/ml). Six replicate slices were prepared per treatment group. A significant reduction in ATP levels was obtained with the treatment of 100 µg/ml anti-extracellular matrix metalloproteinase inducer monoclonal antibody in patients 12, 13, and 15.