Table 2.
Candidate miRNAs to enhance chondrogenesis in MSCs and dedifferentiated chondrocytes.
MicroRNA | Cell type used | Result | Reference |
---|---|---|---|
miR-199a | C3H10T1/2 stem cells | Knockdown of Smad1 | [71] |
miR-675 | Human articular chondrocytes | Enhancement of Collagen II synthesis | [72] |
miR-145 | C3H10T1/2 stem cells | Knockdown of Sox9 | [74, 75] |
miR-21 | Rat articular chondrocytes | Enhancement of chondrocyte proliferation | [76] |
miR-140 | C3H10T1/2 stem cells | Knockdown of ADAMTS-5 and CXCL12 | [77, 78] |