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. 2014 May 18;2014:428371. doi: 10.1155/2014/428371

Table 2.

Oncogenes and oncogenic pathway targets of miR-1 in cancers.

Gene name Genbank accession number Chromosome location Functions Reference number
Met NM_000245.2 7q31 Proto-oncogenic receptor tyrosine kinase [42, 44, 68]
HDAC4 NM_006037.3 2q37.3 Histone deacetylase activity; represses transcription [14, 31, 39]
Pim-1 NM_002648.3 6p21.2 Proto-oncogene [33]
FOXP1 NM_001244810.1 3p14.1 Regulate gene transcription; tumor suppressor [33, 39]
TAGLN2 NM_003564.1 1q21-q25 Earliest marker of differentiated smooth muscle [50, 56, 64]
PNP NM_000270.3 14q13.1 Purine metabolism [50, 58]
PTMA NM_002823.4 2q37.1 Enhance cell-mediated immunity [58]
CXCR4 NM_001008540.1 2q21 Chemokine receptor [65]
CCND2 NM_001759.3 12p13 Regulator of cyclin-dependent kinase [65, 71]
SRSF9 NM_003769.2 12q24.31 [57]
FN1 NM_212482.1 2q34 Involved in cell adhesion, growth, and migration [61]
ETS1 NM_001143820.1 11q23.3 Proto-oncogene [40]
Endothelin 1 NM_001955.4 6p24.1 Involved in vascular disorders [41]
Slug NM_003068.4 8q11 Transcriptional repressor and has antiapoptotic activity [38]
CXCL12 NM_199168.3 10q11.1 Chemotactic for lymphocytes [65]