. Author manuscript; available in PMC: 2014 Aug 1.

Published in final edited form as: Gynecol Oncol. 2013 Apr 28;130(2):334–339. doi: 10.1016/j.ygyno.2013.04.053

Table 3.

Family History of Cancer and Endometrial Cancer Risk by Menopausal Status, 2002-2006, Alberta, Canada.

	All Study Participants (n=1534)			Menopausal Status^b
	Cases (n=519)	Controls (n=1015)	OR (95% CI)^a	Pre- menopausal (n=53 cases; n=122 controls) OR (95% CI)^a	Post- menopausal (n=399 cases; n=732 controls) OR (95% CI)^c
First degree family history of cancer
Uterine	28	44	1.3 (0.8, 2.2)	3.1 (0.5, 17.2)	1.2 (0.7, 2.2)
Colorectal	56	105	1.0 (0.7, 1.5)	2.0 (0.2, 22.0)	1.1 (0.7, 1.7)
UCca	82	143	1.2 (0.9, 1.6)	2.8 (0.7, 11.6)	1.2 (0.8, 1.7)
Lung	50	105	0.9 (0.6, 1.3)	1.0 (0.3, 3.6)	0.9 (0.6, 1.4)
First and second degree family history of cancer
Uterine	61	95	1.3 (0.9, 1.9)	1.4 (0.4, 5.0)	1.2 (0.8, 1.8)
Colorectal	129	251	1.0 (0.8, 1.3)	1.1 (0.4, 3.1)	1.2 (0.9, 1.5)
UCca	174	318	1.1 (0.9, 1.4)	1.4(0.6, 3.4)	1.2 (0.9, 1.6)
Lung	126	252	1.0 (0.7, 1.2)	1.2 (0.5, 3.0)	1.0(0.8, 1.4)

OR, odds ratio; CI, confidence interval; UCca, uterine or colorectal cancer or both.

Adjusted for age (<40, 40-44, 45-49, 50-54, 55-59, 60-64, 65-69, 70-74, 75-79), residence (urban, rural), BMI (<24.9, 25-29.9, >30, unknown), parity (0, 1-2, >3), oral contraception use (never, 6-59, ≥60 months, unknown), number of first degree relatives or number of first and second degree relatives (continuous).

Perimenopausal women (n=227), and women with unknown menstrual status (n=1), were excluded from menopausal status analysis.

Additionally adjusted for hormone therapy (nonusers, CCE+P, other combinations, unknown).