Table 4.
Unadjusted and adjusted associations between WHR, BMI and the composite outcome of incident kidney disease and mortality.
| Predictor | Method | Model | Per unit increase | Per SD increase | ||
|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | |||
| WHR | Creatinine | Unadjusted | 1.54 | 1.45- 1.63 | 1.41 | 1.35- 1.48 |
|
| ||||||
| Adjusted | 1.15 | 1.08- 1.23 | 1.12 | 1.06- 1.18 | ||
|
| ||||||
| eGFR | Unadjusted | 1.45 | 1.37- 1.53 | 1.35 | 1.29- 1.41 | |
|
| ||||||
| Adjusted | 1.11 | 1.04- 1.18 | 1.09 | 1.03- 1.14 | ||
|
| ||||||
| BMI | Creatinine | Unadjusted | 0.99 | 0.97- 1.01 | 0.98 | 0.94- 1.02 |
|
| ||||||
| Adjusted | 0.98 | 0.96- 1.00 | 0.94 | 0.90- 0.99 | ||
|
| ||||||
| eGFR | Unadjusted | 0.99 | 0.97- 1.01 | 0.98 | 0.94- 1.02 | |
|
| ||||||
| Adjusted | 0.97 | 0.95- 0.99 | 0.93 | 0.88- 0.97 | ||
WHR, waist to hip ratio; BMI, body mass index; eGFR, estimated glomerular filtration rate; HR, hazard ratio; CI, confidence interval; SD, standard deviation
One unit increase is 0.1 unit increase in WHR or 1 kg/m2 increase in BMI.
Models adjusted for age, sex, African American race, high school graduation, prior cardiovascular disease, diabetes, hypertension, current smoking and alcohol consumption, systolic blood pressure, HDL and total cholesterol, albumin, hematocrit, baseline kidney function, and study of origin