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. 2014 May 8;15(6):2090–2103. doi: 10.1021/bm500224f

Table 1. Proliferation and Protein Expression of Proliferative and Quiescent SMCs Treated with PDGF or IFN-γ and DS-SILY₂₀.

	proliferation (cells/mm³)		protein expression (fluorescence/cell (×10³))
treatment	proliferative SMC	quiescent SMC	proliferative SMC	quiescent SMC
no treatment	15.3 ± 0.7^b	6.8 ± 0.4^b^,^c	71.7 ± 4.8^b^,^c	34.1 ± 1.8^b^,^c
10 μM DS-SILY₂₀	11.5 ± 1.3^b	6.2 ± 0.5^b^,^c	59.9 ± 5.0^a^,^b	32.8 ± 1.3^b^,^c
10 ng/mL PDGF + μM DS-SILY₂₀
0	19.1 ± 1.2^a	9.6 ± 0.8^a	86.3 ± 10.3^a	45.3 ± 4.3^a
0.01	17.9 ± 1.7^a	8.9 ± 0.8^a	78.9 ± 3.8^a	33.3 ± 2.7^b
0.1	16.9 ± 0.8^b	7.9 ± 0.6^b	72.3 ± 4.7	28.7 ± 3.5^b
1	15.8 ± 1.2^b	7.4 ± 0.3^b	68.4 ± 4.6^b	26.2 ± 2.3^a^,^b
10	14.8 ± 1.4^b	6.9 ± 0.7^b	63.3 ± 3.7^b	23.0 ± 2.6^a^,^b
10 ng/mL IFN-γ + μM DS-SILY₂₀
0	15.1 ± 1.1	9.3 ± 1.0^a	55.0 ± 9.4^a	61.5 ± 4.3^a
0.01	14.3 ± 2.7	9.2 ± 0.6^a	55.5 ± 8.3^a	52.9 ± 7.4^a
0.1	14.2 ± 0.8	9.0 ± 0.7^a	49.1 ± 4.2^a	53.4 ± 2.5^a^,^c
1	14.8 ± 1.1	8.8 ± 0.9^a	45.5 ± 5.6^a	45.^a^,^c4 ± 4.3
10	13.5 ± 0.6^a	8.1 ± 1.1	42.4 ± 4.5^a	39.4 ± 1.6^a^,^c

^a

Significance from no treatment control cultures.

^b

Significance from PDGF-stimulated SMC cultures.

^c

Significance from IFN-γ stimulated SMC cultures.