Table 3. Comparison of rates of psychiatric disease between manifesting carrier, non-manifesting carrier and tremor groups.
| Psychiatric diagnosis (DSM-IV) | MC versus tremor | NMC versus tremor | MC versus NMC |
|---|---|---|---|
| Any | 0.20 (2.13; 0.64, 7.31) | 0.29 (0.41; 0.08, 1.96) | 0.05 (5.25; 0.88, 34.12) |
| Major depressive disorder | 1.0 (1.0; 0.34, 2.91) | 1.0 (0.83; 0.17, 4.02) | 1.0 (1.2; 0.22, 6.70) |
| Mania and hypomania | 0.29 (0; 0, 3.8) | 1.0 (0; 0, 11.37) | 1.0 (unable to calculate) |
| Panic disorder | 0.8 (0.82; 0.27, 2.51) | 0.14 (0.18; 0.01, 1.67) | 0.23 (4.5; 0.44, 109.94) |
| Agoraphobia | 0.54 (1.55; 0.39, 6.08) | 0.33 (0; 0, 3.63) | 0.16 (∞; 0.40, ∞) |
| Social phobia | 0.03 (3.7; 1.12, 12.56) | 0.33 (0; 0, 3.03) | 0.02 (∞; 1.23, ∞) |
| OCD | 0.001 (6.7; 2.02, 23.27) | 0.33 (0; 0, 3.03) | 0.002 (∞; 2.20, ∞) |
| Alcohol dependence/abusea | 0.02 (4.33; 1.08, 18.06) | 0.58 (0; 0, 4.46) | 0.03 (∞; 0.94, ∞) |
| Psychotic and mood disorders | 1.00 (0.54; 0.02, 6.36) | 1.00 (0; 0, 11.37) | 1 (∞; 0.02, ∞) |
| Generalized anxiety disorder | 0.02 (3.71; 1.16, 12.22) | 0.67 (0.44; 0.02, 4.36) | 0.06 (8.36; 0.84, 201.48) |
Results analysed using chi-squared testing.
Results expressed as: P-value (odds ratio, 95% confidence interval).
Statistically significant results highlighted in bold.
a
Only participants aged >18 years included in analysis.
MC = manifesting carrier; NMC = non-manifesting carrier; OCD = obsessive-compulsive disorder.