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. 2014 May 13;2014:872139. doi: 10.1155/2014/872139

Table 2.

Mechanism of action of glycyrrhizin compound chemotherapy.

Compound Pharmacological activities Mechanisms of action Reference
Glycyrrhizic acid Anti-inflammatory
antiviral
inhibition of hepatic fibrosis
Regulating the expression of inflammation-related factors;
inhibition replication of viral mRNA
[4649]
[51, 59]
[45]

Compound glycyrrhizin tablet Improving the liver dysfunction
augmented the entire cytotoxic function mediated by hepatic lymphocytes
inhibiting the cascade leading to apoptosis
Regulating the expression of inflammation-related factors;
promoting the growth of hepatocyte;
inhibition replication of viral mRNA
[60]
[61]
[62]

Glycyrrhetinic acid Anti-inflammatory
antiviral
antiallergic
antitumor proliferation
Regulating the expression of inflammation-related factors;
inhibition replication of viral;
inhibition of the expression of sensitizing factors and tumor-associated factor;
[63]
[64]
[65]
[66]

18β-glycyrrhetic acid Antiviral
anti-inflammatory
Regulating the expression of inflammation-related factors;
inhibition replication of viral mRNA
[67]

Diammonium glycyrrhizinate Anti-inflammatory, resistance to biologic oxidation and membranous protection
neuroprotective effect
Regulating the expression of inflammation-related factors;
regulating the enzymatic reactions' related oxidation
[68]

Dipotassium glycyrrhizinate Anti-inflammatory Regulating the expression of inflammation-related factors [69]