Table II.
Blood pressure (mm Hg) and heart rate (bpm) of each patient during the observation period (weeks −8 to 0) and the efonidipine treatment period (weeks 0 to 12).
| Study Week |
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| −8 |
−4 |
0 |
4 |
8 |
12 |
|||||||||||||
| Patient No. | SBP | DBP | HR | SBP | DBP | HR | SBP | DBP | HR | SBP | DBP | HR | SBP | DBP | HR | SBP | DBP | HR |
| 1 | 141 | 67 | 93 | 103 | 59 | 91 | 137 | 70 | 91 | 141 | 83 | 85 | 141 | 73 | 88 | 166 | 75 | 78 |
| 2 | 135 | 95 | 92 | 120 | 101 | 86 | 122 | 87 | 100 | 154 | 103 | 90 | 128 | 92 | 88 | 144 | 103 | 97 |
| 3 | – | – | – | 114 | 76 | 88 | 130 | 85 | 87 | – | – | – | 123 | 85 | 80 | – | – | – |
| 4 | 148 | 89 | 81 | 136 | 81 | 88 | 136 | 84 | 87 | 127 | 86 | 72 | 149 | 96 | 74 | 149 | 84 | 72 |
| 5 | 135 | 85 | 101 | 137 | 83 | 96 | 146 | 88 | 103 | 148 | 96 | 82 | 145 | 96 | 90 | 164 | 95 | 71 |
| 6 | 117 | 77 | 108 | 122 | 81 | 96 | 132 | 84 | 93 | 125 | 92 | 94 | 130 | 91 | 88 | – | – | – |
| 7 | 133 | 86 | 105 | 139 | 98 | 119 | 128 | 97 | 111 | 123 | 94 | 88 | – | – | – | – | – | – |
| 8 | 116 | 63 | 93 | 118 | 99 | 92 | 121 | 75 | 95 | 106 | 66 | 82 | 131 | 87 | 84 | 88 | 72 | 80 |
| 9 | – | – | – | 116 | 83 | 91 | 108 | 71 | 102 | 135 | 89 | 93 | 113 | 79 | 97 | 146 | 97 | 103 |
| 10 | – | – | – | 149 | 93 | 96 | 155 | 77 | 87 | – | – | – | 142 | 66 | 83 | 143 | 73 | 91 |
| 11 | 142 | 89 | 81 | 139 | 91 | 88 | 141 | 91 | 93 | 128 | 91 | 92 | 148 | 95 | 101 | – | – | – |
| 12 | 147 | 95 | 91 | 133 | 94 | 89 | 153 | 105 | 97 | 151 | 111 | 99 | 151 | 89 | 66 | 139 | 84 | 94 |
| 13 | 135 | 96 | 83 | 121 | 86 | 104 | – | – | – | 146 | 91 | 85 | – | – | – | – | – | – |
| 14 | 145 | 82 | 89 | 116 | 80 | 100 | 134 | 79 | 92 | 149 | 87 | 92 | 154 | 80 | 86 | 159 | 88 | 76 |
| 15 | 156 | 80 | 107 | 174 | 100 | 96 | 141 | 86 | 107 | 140 | 84 | 94 | 146 | 77 | 91 | 130 | 76 | 90 |
| 16 | 142 | 78 | 88 | 160 | 75 | 85 | 150 | 79 | 83 | 164 | 81 | 83 | 147 | 61 | 89 | 124 | 64 | 87 |
| 17 | 143 | 84 | 91 | 166 | 98 | 113 | 147 | 82 | 91 | 159 | 73 | 89 | 123 | 63 | 93 | 132 | 69 | 103 |
| 18 | 135 | 84 | 70 | 119 | 88 | 80 | 144 | 85 | 92 | 146 | 101 | 74 | 144 | 79 | 79 | 142 | 95 | 76 |
SBP = systolic blood pressure (normal value, ≤140 mm Hg); DBP = diastolic blood pressure (normal value, ≤90 mm Hg); HR = heart rate (normal value, ≤70 bpm).