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Crystal structure of BlaC–tebipenem covalent adduct. (A) Overall structure of BlaC with the tebipenem covalent adduct displayed by atom color (resolution 1.9 Å). (B) Fo – Fc omit map of the BlaC–tebipenem covalent adduct formed at the active site residue Ser70 contoured at 2.0σ. (C) Active site of BlaC–tebipenem covalent adduct showing interactions and interatomic distances between tebipenem and active site residues.
