Table 1.
QSOX1 mRNA expression in relation to the usual prognostic factors in 217 breast IDC
| Characteristics | n | % | median | P-value | |
|---|---|---|---|---|---|
| Menopausal status | Pre | 71 | 32.7 | 2.56 | |
| Post | 146 | 67.3 | 3.31 | 0.003 | |
| Tumor size (mm) | <20 | 90 | 41.5 | 3.08 | |
| ≥20 | 120 | 55.3 | 2.62 | 0.229 | |
| ND | 7 | 3.2 | 3.38 | ||
| Lymph node status | pN0 | 101 | 46.5 | 3.18 | |
| pN+ | 116 | 53.5 | 2.64 | 0.444 | |
| SBR Grade | I | 30 | 13.8 | 4.25 | |
| II | 115 | 53.0 | 3.14 | ||
| III | 58 | 26.7 | 1.74 | <0.001 | |
| ND | 14 | 6.5 | 2.42 | ||
| ER status | Positive | 179 | 82.5 | 3.17 | |
| Negative | 38 | 17.5 | 1.51 | <0.001 | |
| PgR status | Positive | 169 | 77.9 | 3.17 | |
| Negative | 48 | 22.1 | 1.97 | <0.001 | |
| PAI-1 status* | Low | 153 | 70.5 | 3.18 | |
| High | 44 | 20.3 | 1.46 | <0.001 | |
| ND | 20 | 9.2 | 2.77 | ||
P-values correspond to Mann-Whitney test or Kruskall Wallis test. ER, estrogen receptor; ND, Not Determined; PgR, Progesteron receptor; SBR, Scarff Bloom Richardson. *Low: ≤75% quartile; High: >75% quartile.