Table 4.
Correlations between WIF1/SFRP1 protein expression and clinical characteristics of CRC patients.
| Characteristics | Cases (N = 127) |
Immunoreactive positive (%) | |||
|---|---|---|---|---|---|
| WIF1 | P value | SFRP1 | P value | ||
| Age (year) | 0.652 | 0.704 | |||
| ≤65 | 66 | 49 (74.2) | 28 (42.4) | ||
| >65 | 79 | 56 (70.9) | 36 (45.6) | ||
| Gender | 0.273 | 0.115 | |||
| Male | 80 | 55 (68.8) | 40 (50.0) | ||
| Female | 65 | 50 (76.9) | 24 (36.9) | ||
| Lesion sites | 0.704 | 0.000 | |||
| Right | 87 | 62 (71.3) | 49 (56.3) | ||
| Left | 58 | 43 (74.1) | 15 (25.9) | ||
| Architectural features | 0.488 | 0.835 | |||
| Mucus | 15 | 12 (80.0) | 7 (46.7) | ||
| Nonmucinous | 130 | 93 (71.5) | 57 (43.8) | ||
| Tumor diameter | 0.005 | 0.250 | |||
| ≤4.5 cm | 67 | 41 (61.2) | 33 (49.3) | ||
| >4.5 cm | 78 | 64 (82.1) | 31 (39.7) | ||
| Invasion | 0.001 | 0.025 | |||
| T1 | 6 | 2 (33.3) | 5 (83.3) | ||
| T2 | 19 | 15 (78.9) | 9 (47.4) | ||
| T3 | 41 | 22 (53.7) | 23 (56.1) | ||
| T4 | 79 | 66 (83.5) | 27 (34.2) | ||
| Lymph metastasis | 0.096 | 0.132 | |||
| N0 | 84 | 61 (72.6) | 43 (51.2) | ||
| N1 | 24 | 21 (87.5) | 8 (33.3) | ||
| N2 | 37 | 23 (62.2) | 13 (35.1) | ||
| Liver metastasis | 0.703 | 0.109 | |||
| Negative | 132 | 95 (72.0) | 61 (46.2) | ||
| Positive | 13 | 10 (76.9) | 3 (23.1) | ||
| TNM stagea | 0.878 | 0.042 | |||
| I | 29 | 21 (72.4) | 16 (55.2) | ||
| II | 52 | 39 (75.0) | 27 (51.9) | ||
| III | 47 | 34 (72.3) | 18 (38.3) | ||
| IV | 17 | 11 (64.7) | 3 (17.6) | ||
aAccording to the 2002 version of the American Joint Committee on Cancer (AJCC) and the International Union Against Cancer (UICC).