Table 2.
Effect of BHE on hepatic marker enzymes after 6 weeks of CCl4 intoxication in mice.
| Animal groups | ALT (U/L) | AST (U/L) | ALP (IU/L) |
|---|---|---|---|
| Control | 13.23 ± 0.71$ | 122.40 ± 2.68$ | 81.06 ± 4.73$ |
| CCl4 | 43.25 ± 3.05* | 223.30 ± 5.32* | 143.65 ± 3.82* |
| BHE (500 mg/kg/day) | 24.29 ± 2.60#
(44%) |
142.84 ± 5.45#
(36%) |
104.14 ± 5.44#
(28%) |
| BHE (1000 mg/kg/day) | 15.76 ± 2.72$#
(64%) |
120.24 ± 5.83$
(46%) |
83.76 ± 5.86$#
(42%) |
| Silymarin (500 mg/kg/day) |
23.64 ± 2.25#
(45%) |
125.06 ± 3.43$#
(44%) |
89.78 ± 5.24$#
(38%) |
Data are expressed as the means ± SEM, (n = 9).
The numbers in parentheses represent the percentage of reduction from the CCl4-intoxicated group.
Values having different superscripts within the same column are significantly different at P < 0.05.