Table 2.
Antileishmanial activity of crude extracts and compounds isolated from Canarium patentinervium Miq. against Leishmania donovani promastigotes.
| Samples | IC50 (μg/mL) |
|---|---|
| Hexane extract of leaves | 257.40 ± 0.30 |
| Chloroform extract of leaves | 457.70 ± 0.25 |
| Ethanol extract of leaves | >500 |
| Hexane extract of barks | 284.20 ± 0.40 |
| Chloroform extract of barks | 359.90 ± 0.20 |
| Ethanol extract of barks | >500 |
| Scopoletin | 163.30 ± 0.32 |
| Scoparone | 329.90 ± 0.32 |
| (+)-Catechin | 478.93 ± 0.28 |
| Vomifoliol | 302.80 ± 0.33 |
| Lioxin | 211.48 ± 0.32 |
| Syringic acid | nt |
| Amphotericin B | 0.37 ± 0.10 |
Data were obtained from three independent experiments, each performed in triplicates (n = 9) and represented as mean ± SD. Values with the same capital letter are not significantly different (P < 0.01) according to Tukey multiple comparison test, nt: not tested.