Table 1.
Incidence of testicular tumors and testicular abnormalities in the congenic strains
| Mouse strains | % TGCTs | No. with TGCT | % (no.) unilateral TGCTs | % (no.) bilateral TGCTs | % (no.) abnormal testes | No. of males examined |
|---|---|---|---|---|---|---|
| *129 |
5% |
4 |
5% (4) |
0 |
15% (12) |
83 |
| *M19 |
71% |
85 |
39% (46) |
33% (39) |
5% (6) |
119 |
|
Single congenics | ||||||
| 5 |
4% |
4 |
3% (3) |
1% (1) |
24% (23) |
96 |
| 6 |
19% |
25 |
16% (21) |
3% (4) |
26% (35) |
134 |
| *3 |
32% |
26 |
21% (18) |
10% (8) |
9% (7) |
82 |
| *B-81 |
4% |
5 |
4% (5) |
0 |
10% (13) |
129 |
| 7 |
14% |
18 |
12% (16) |
2% (2) |
5% (7) |
133 |
|
Double congenics | ||||||
| 5 × 3 |
34% |
47 |
26% (35) |
9% (12) |
12% (17) |
137 |
| 5 × B-81 |
11% |
14 |
9% (12) |
2% (2) |
16% (21) |
133 |
| 5 × 7 |
8% |
11 |
8% (10) |
1% (1) |
14% (18) |
130 |
| 6 × B-81 |
10% |
9 |
10% (9) |
0 |
15% (13) |
88 |
| 1 |
22% |
38 |
20% (35) |
2% (3) |
6% (10) |
171 |
| 3 × 7 |
26% |
32 |
18% (22) |
8% (10) |
11% (13) |
122 |
|
Triple congenic | ||||||
| 5 × 3× 7 | 37% | 50 | 30% (40) | 7% (10) | 8% (11) | 136 |